Centre for Continuing Education

Agomelatine in the Management of Depression Course Online

Psychiatry. Encouraging a healthier community.

Developed and delivered by the Discipline of Psychiatry at Sydney Medical School, the University of Sydney, and open to all health professionals for continuing professional development.

Join this self-paced interactive online course to learn the circadian model of depression and the latest pharmacological treatment based on this model.

Depression is a biopsychosocial illness. Studies of global burden of disease suggest that by 2020, major depressive disorder will represent the second leading cause of Disability-Adjusted Life Years lost globally, just behind ischaemic heart disease. There are a number of theoretical models to understand why people get depressed. Each of these models has its own mechanism and treatments. This course will focus on the circadian model and teach you how we can use agomelatine to manipulate patients' circadian rhythm in order to achieve better treatment outcomes from both patients' perspective and medical practitioners' perspective.

This course accepts enrolments throughout the year and does not have any prerequisite requirements.


By the end of this course, you should be able to:

  • describe the mechanism of the circadian model of depression
  • compare agomelatine to other antidepressants
  • demonstrate an understanding of patients' desired treatment outcomes for depression
  • explain how to measure and minimise patients' emotional blunting during treatment of depression.


This course covers the following topics:

  • Circadian rhythms and depression
  • Antidepressant efficacy and effectiveness with a focus on agomelatine
  • Emotional blunting and antidepressants
  • The RANZCP mood disorders guidelines, rating evidence, meta-analyses and agomelatine.

Delivery style

Delivered in an e-learning system with the following components:

  • social chat forum where you can introduce yourself to the class and organise local meet-up groups
  • Q & A forum where you can ask questions and get feedback from the tutor and other participants
  • multimedia modules with audio-visual lectures and interactive quizzes
  • lecture notes download
  • lecture audios download
  • assessment task
  • Statement of Completion download.

You will have 90 days to complete the course at your own pace. It takes approximately 3 hours to complete it. Within the enrolment period, access to the e-learning system is available anytime and anywhere in the world as long as you have a reliable and high speed Internet connection.

The lecture audios were recorded in a professional studio and are of high quality. You can download them to your mobile devices and continue to listen to the course while travelling.

CPD Accreditation

  • Royal Australian College of General Practitioners (RACGP): 6 Category 2 points
  • Australian College of Rural & Remote Medicine (ACRRM): 3 Core points


We acknowledge Professor Malcolm Hopwood and Professor David Castle from the University of Melbourne for their contributions to the development of this online course.


  • Convenient online access
  • Mobile learning supported
  • High quality course audios
  • Expert academic support
  • Statement of Completion

We acknowledge the tradition of custodianship and law of the Country on which the University of Sydney campuses stand. We pay our respects to those who have cared and continue to care for the Country.